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Neural and Physiological Mechanisms Supporting Mindfulness-Based Analgesia as Compared to Placebo

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This webinar - held on 2 May 2024 - was produced through a collaboration of the IASP's Pain and Placebo Special Interest Group and the University of Maryland, Baltimore, USA - in particular - the University of Maryland School of Nursing's Placebo Beyond Opinions Center. Both groups are aligned on advancing unbiased knowledge of placebo effects by promoting interdisciplinary investigation of the placebo phenomenon and nurturing placebo research.
                                                                                     
The IASP defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage" to better articulate the biopsychosocial dimensions of this phenomenon. While our understanding of pain has greatly evolved over the past decades, there are still fundamental questions that need to be addressed, including its psychological components.

Various analyses indicate mindfulness-based meditation to be efficacious for chronic and acute pain management, however, most available studies lack appropriate controls. As such, placebo-related processes could account for these positive mindfulness effects. Therefore, a mechanistic understanding of mindfulness processes is required to disentangle the analgesic effects of mindfulness from placebo-related processes. In this webinar, we took a deep-dive into the neural and physiological mechanisms supporting mindfulness-based analgesia that distinguish this treatment from placebo-related processes.


Participants included:

--
Fadel Zeidan, PhD, University of California, San Diego, USA
-- Luana Colloca, MD, PhD, University of Maryland School of Nursing, USA (host)

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