2022 IADR/APR General Session
The 100 th General Session & Exhibition of the IADR was held in conjunction with the 5th Meeting of the Asia Pacific Region. The virtual meeting was attended by individuals from around the world. Those attending the meeting could choose from among 207 Interactive Talk sessions, seven Focused Learning Sessions, three Hands-on Workshops, five satellite symposia, 52 Symposia, one Distinguished Lecture Series and a plenary.The recordings in this library from the meeting are a selection of the science that was to be presented as part of the General Session. These recordings give you the opportunity to participate in the meeting and hear from leading researchers. The recordings include the IADR Distinguished Lecture Series speaker and symposia from a collection of scientific groups and networks.
This session can be purchased as part of the full meeting recordings within the product bundles
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Session Description
Being a sequel of endodontic infection, apical periodontitis (AP) is the most prevalent inflammatory lesion of the jaws. Since the jaws through the teeth are in direct connection to the bone marrow with no epithelial barriers that could limit the spread of the infection, the immunological response plays a pivotal role in restraint endodontic microbiome invasion into other tissues. On one side, bacterial pathogenic properties such as antigenicity, mitogenicity activity, chemotaxis, enzymatic histolysis, and on the other hand the defense molecules of the organism such as immune cells products and intercellular messengers take part in a battle with the final result as the destruction of the periapical tissues. Conventional endodontic treatment includes the use of antimicrobial agents such as sodium hypochlorite, chlorhexidine, and calcium hydroxide, however, the use of these agents increases bacterial resistance resulting in persistent flare-ups. In the past few years, alternative pharmacologic therapies are being tested to try to solve the immune-inflammatory response of AP. Some studies include the use of biological medications such as monoclonal antibodies that target specific proteins to block the inflammatory process like TNF-alfa inhibitors, lymphocyte, and interleukin modulators. Other studies perform autologous transplantation of dental pulp stem cells to regenerate pulp tissue after disinfection of root canals. Another group of research revealed the positive outcome of Specialized Pro Resolving Lipid Mediators (SPMs) as intracanal medication to stimulate healing in AP using animal models. This session aims to discuss modern alternative therapies for the treatment of apical periodontitis.
Learning Objectives
Presentation Date
June 24, 2022
Presenters
Claudia Brizuela - Encapsulated Allogenic Cell-Based Therapy for Apical Periodontitis
Yasir Siddiqui - RVD2 reverses Periapical Inflammation to Tissue Regeneration Renan Dal Fabbro - Apical Periodontitis, Polyphenols, and Wine. a Promising Pathway
Sponsoring Groups/Networks
Pulp Biology & Regeneration Research
CE Credits
1.5 Hours
Financial Interest Disclosure:
None
Being a sequel of endodontic infection, apical periodontitis (AP) is the most prevalent inflammatory lesion of the jaws. Since the jaws through the teeth are in direct connection to the bone marrow with no epithelial barriers that could limit the spread of the infection, the immunological response plays a pivotal role in restraint endodontic microbiome invasion into other tissues. On one side, bacterial pathogenic properties such as antigenicity, mitogenicity activity, chemotaxis, enzymatic histolysis, and on the other hand the defense molecules of the organism such as immune cells products and intercellular messengers take part in a battle with the final result as the destruction of the periapical tissues. Conventional endodontic treatment includes the use of antimicrobial agents such as sodium hypochlorite, chlorhexidine, and calcium hydroxide, however, the use of these agents increases bacterial resistance resulting in persistent flare-ups. In the past few years, alternative pharmacologic therapies are being tested to try to solve the immune-inflammatory response of AP. Some studies include the use of biological medications such as monoclonal antibodies that target specific proteins to block the inflammatory process like TNF-alfa inhibitors, lymphocyte, and interleukin modulators. Other studies perform autologous transplantation of dental pulp stem cells to regenerate pulp tissue after disinfection of root canals. Another group of research revealed the positive outcome of Specialized Pro Resolving Lipid Mediators (SPMs) as intracanal medication to stimulate healing in AP using animal models. This session aims to discuss modern alternative therapies for the treatment of apical periodontitis.
Learning Objectives
- To learn modern alternative therapies to treat apical periodontitis
- To describe the advantages and disadvantages of the newest therapies used for the treatment of apical periodontitis
- To describe how modern endodontic therapies work at the molecular level.
Presentation Date
June 24, 2022
Presenters
Claudia Brizuela - Encapsulated Allogenic Cell-Based Therapy for Apical Periodontitis
Yasir Siddiqui - RVD2 reverses Periapical Inflammation to Tissue Regeneration Renan Dal Fabbro - Apical Periodontitis, Polyphenols, and Wine. a Promising Pathway
Sponsoring Groups/Networks
Pulp Biology & Regeneration Research
CE Credits
1.5 Hours
None
Not eligible for individual purchase; must purchased as part of a meeting bundle.
